Some people are allergic to a substance and does not know. Some people have a body that no longer tolerates a certain amount of substances. And yet, there are diseases that not all contract the same way that the care, not always, are universal.
Bugiardini The drugs are the same for everyone, but the sick are not all equal. And therapies drug do not react all the same way some people respond well and recover, but some - unfortunately - we leave the pens. For an allergic reaction to an incorrect dose. The solution is to create drugs "ad personam", made to measure for the patient. It would seem fatascienza, but - giving scientists Sacco Hospital where he was yesterday presented the new Pharmacology Unit that will make this new frontier his forte - it is not at all.
'Responses of patients to drugs - said Paul Clements, director of Unity - are increasingly unpredictable, " so that so-called adverse drug reactions are the fourth leading cause of death worldwide. In the last year, in sixteen hospitals in Lombardy, the region has spent twenty million euro drug therapies to correct wrong or treat people who have experienced adverse reactions.
"It is therefore increasingly necessary to create a personalized care." But how do you strike up a measure of patient therapy? Pharmacogenetics is an answer and right in the bag, birth of the first railway built in Italy with a system that will test the DNA of patients to find the ad hoc therapy: in essence it comes to studying what we have more staff, that is our mapping of DNA, to understand how genes interact with the product: "Working on these associations will allow us to measure the variability of drug response, thereby removing, in essence, the side effect linked to the individual patient and" optimizing care. Through pharmacovigilance, then, we monitor the effects. " The new Clinical Pharmacology
Sacco, an agreement with the University of Milan, will have its new building in 2010: four floors of research carried out in specialized laboratories and test beds for new drugs that will attract the search industry pharmaceutical and biomedical companies in Lombardy. Investment, which cost two million to Pirellone euro, medical workers, pharmacists, biologists, biotechnologists, chemical and pharmaceutical chemicals.
A 'turning point, "says Virgilio Ferrario, Dean of the Faculty of Medicine of the State:' It's important to talk not only of drugs designed for the type of disease, but also for the type of patient you wish to treat. The medicine of the future must involve the discussion of the disease on the person. Because if 90 percent is related to drug therapy itself, the ten percent is based on knowledge of the subject. "
The team of Professor Clements is already at work. Since September, he says, have already been tested about eight to ten people between the departments of oncology and Infectious Diseases: "The patient with an adverse drug reaction comes from us. By a levy, we measure the amount of drug in the blood and indicate the right dosage. " A first step towards the "personalization of medicine" by Roberto Formigoni hoped that in future, will allow citizens "to have a" card megnetica "with their own genetic characteristics, a kind of ATM's health."
0 comments:
Post a Comment